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Related post: already quoted there is some diflSculty in explaining the
phenomenon ; why the bone-conduction is not always aug-
mented by means used to relieve pressure on the labyrinth,
as, for instance, pushing out a sunken drum-membrane by
inflation, does not appear. If pressure is the sole cause of
the deafness in such cases, it would seem that relief of press-
ure should place the nerve in better condition to appreciate
bone-conduction, as the aerial conduction has been im-
proved. On the other hand, if the cause of the deafness
exists in the badly vibrating middle-ear mechanism due to
the crowding together of the ossicles, placing the membrana
tympani on the stretch, then the improved bone-conduction
resulting from inflation should be constant, which is very
far from being the case. In this instance we adopt the
theory that bone-conduction is improved Buy Myambutol or diminished by
the good or bad vibratory condition of the middle-ear
mechanism. Neither of these theories seems to be tenable.
It may be worthy of remark that, from a theoretical point
of view, we might expect weakened bone-conduction in
every case of lowered hearing from any cause whatever.
It is not in the least a matter of wonder that changes re-
sult in cases of tolerably pure middle-ear disease, which pro-
duce disturbances in the function of the acusticus, and con-
sequently give the tuning-fork reaction of labyrinthine dis-
ease. In any case of permanent impaction of the stapes in
the oval window consequent on middle-ear disease there
must needs be pressure on the perilymph. Thickening of
the membrane of the round window will accomplish the
same thing, but in a less degree.
In syphilitic middle-ear disease we are likely to have
similar conditions, only greatly exaggerated, the tendency
to inflammatory proliferation, as is well known, being much;
stronger than in non-specific cases, and the structural
changes will be proportionately greater. It may also ac-
count for the prompt improvement in hearing under a rapid
course of mercury. It is by no means denied, however, that
the more usual syphilitic lesions are for the most part laby-
rinthine. All of these conditions are likely, but are not
certain, to result in weakened bone-conduction, and add the
element of labyrinthine disease to the middle-ear affection.
Summary. — I conclude that the greatest amount of
bone-conduction proceeds from a normal ear closed, and
that the principal diagnostic sign of labyrinthine disease
appears in weakened bone-conduction.
That the apparent increase of bone-conduction in mid-
dle-ear disease will disappear when the test is made witb
the ear closed, when it will be found not to exceed that of
the normal ear. In those cases called " mixed " the bone-
conduction will be found weakened when the test is made
with the ear closed, although with both ears open the af-
fected one may have better bone-conduction than its fellow.
That, so far, it seems that the good or bad condition of
the middle-ear mechanism has little influence on bone-con-
duction.
That the occasional phenomenon of intermittent bone-
conduction can not be satisfactorily explained.
That cases of pure labyrinthine disease can not always
be distinguished from those of middle- ear aflfections with
secondary labyrinthine changes by the tuning-fork^ and that
the history of the cases must materially aid us in the dis-
tinction.
That the phenomenon of secondary labyrinthine changes
in middle-ear diseases is easily explainable.
That there are numerous exceptions to the rules for
finding the best points on the head for eliciting bone-con-
duction.
That the bone-conduction is rarely or never of less thaa
its proper ratio to aerial conduction.
AN EXAMINATION OF THE EYES OF
FIFTY CASES OF CHOREA OF CHILDHOOD.
By G. E. DE SCHWEINITZ, M. D. (Univ. of Penn.),
OPHTHALMIC SURGEON TO THE PHILADELPHIA HOSPITAL, TO THE CHILDREN'S
HOSPITAL, AND TO THE INFIRMARY TOR NERVOUS DISEASES.
The cases of chorea from which this study has been made
have for the most part been those of patients in attendance at
the clinics of Dr. S. Weir Mitchell, Dr. Wharton Sinkler, and
Dr. William Osier in the Infirmary for Nervous Diseases-
Certain results which should naturally be the outcome of
the examinations which follow are not set down, because
suflBcient time has not yet elapsed to render this possible.
The following points have received special attention : The
chromatic symmetry or asymmetry of the irides, the devel-

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